Infectious disease: acute episode, mild 0.005 0.002-0.011 Infectious disease: acute episode, moderate 0.053 0.033-0.081 Infectious disease: acute episode, severe 0.21 0.139-0.298 Infectious disease: post-acute consequences (fatigue, emotional lability, insomnia) 0.254 0.170-0.355 Diarrhoea: mild 0.061 0.036-0.093 Diarrhoea: moderate 0.202 0.133-0.299 Diarrhoea: severe 0.281 0.184-0.399 Epididymo-orchitis 0.097 0.063-0.137 Herpes zoster 0.061 0.039-0.094 HIV: symptomatic, pre-AIDS 0.221 0.146-0.310 HIV/AIDS: receiving antiretroviral treatment 0.053 0.034-0.079 AIDS: not receiving antiretroviral treatment 0.547 0.382-0.715 Intestinal nematode infections: symptomatic 0.03 0.016-0.048 Lymphatic filariasis: symptomatic 0.11 0.073-0.157 Ear pain 0.018 0.009-0.031 Tuberculosis: without HIV infection 0.331 0.222-0.450 Tuberculosis: with HIV infection 0.399 0.267-0.547 Cancer: diagnosis and primary therapy 0.294 0.199-0.411 Cancer: metastatic 0.484 0.330-0.643 Mastectomy 0.038 0.022-0.059 Stoma 0.086 0.055-0.131 Terminal phase: with medication (for cancers, end-stage kidney or liver disease) 0.508 0.348-0.670 Terminal phase: without medication (for cancers, end-stage kidney or liver disease) 0.519 0.356-0.683 Acute myocardial infarction: days 1-2 0.422 0.284-0.566 Acute myocardial infarction: days 3-28 0.056 0.035-0.082 Angina pectoris: mild 0.037 0.022-0.058 Angina pectoris: moderate 0.066 0.043-0.095 Angina pectoris: severe 0.167 0.109-0.234 Cardiac conduction disorders and cardiac dysrhythmias 0.145 0.097-0.205 Claudication 0.016 0.008-0.028 Heart failure: mild 0.037 0.021-0.058 Heart failure: moderate 0.07 0.044-0.102 Heart failure: severe 0.186 0.128-0.261 Stroke: long-term consequences, mild 0.021 0.011-0.037 Stroke: long-term consequences, moderate 0.076 0.050-0.110 Stroke: long-term consequences, moderate plus cognition problems 0.312 0.211-0.433 Stroke: long-term consequences, severe 0.539 0.363-0.705 Stroke: long-term consequences, severe plus cognition problems 0.567 0.394-0.738 Diabetic foot 0.023 0.012-0.039 Diabetic neuropathy 0.099 0.066-0.145 Chronic kidney disease (stageIV) 0.105 0.069-0.154 End-stage renal disease: with kidney transplant 0.027 0.015-0.043 End-stage renal disease: on dialysis 0.573 0.397-0.749 Decompensated cirrhosis of the liver 0.194 0.127-0.273 Gastric bleeding 0.323 0.214-0.461 Crohn’s disease or ulcerative colitis 0.225 0.152-0.314 Benign prostatic hypertrophy: symptomatic 0.07 0.046-0.102 Urinary incontinence 0.142 0.094-0.204 Impotence 0.019 0.010-0.034 Infertility: primary 0.011 0.005-0.021 Infertility: secondary 0.006 0.002-0.013 Asthma: controlled 0.009 0.004-0.018 Asthma: partially controlled 0.027 0.015-0.045 Asthma: uncontrolled 0.132 0.087-0.190 COPD and other chronic respiratory diseases: mild 0.015 0.007-0.028 COPD and other chronic respiratory diseases: moderate 0.192 0.129-0.271 COPD and other chronic respiratory diseases: severe 0.383 0.259-0.528 Dementia: mild 0.082 0.055-0.117 Dementia: moderate 0.346 0.233-0.475 Dementia: severe 0.438 0.299-0.584 Headache: migraine 0.433 0.287-0.593 Headache: tension-type 0.04 0.025-0.062 Multiple sclerosis: mild 0.198 0.137-0.278 Multiple sclerosis: moderate 0.445 0.303-0.593 Multiple sclerosis: severe 0.707 0.522-0.857 Epilepsy: treated, seizure free 0.072 0.047-0.106 Epilepsy: treated, with recent seizures 0.319 0.211-0.445 Epilepsy: untreated 0.42 0.279-0.572 Epilepsy: severe 0.657 0.464-0.827 Parkinson’s disease: mild 0.011 0.005-0.021 Parkinson’s disease: moderate 0.263 0.179-0.360 Parkinson’s disease: severe 0.549 0.383-0.711 Alcohol use disorder: mild 0.259 0.176-0.359 Alcohol use disorder: moderate 0.388 0.262-0.529 Alcohol use disorder: severe 0.549 0.384-0.708 Fetal alcohol syndrome: mild 0.017 0.008-0.032 Fetal alcohol syndrome: moderate 0.057 0.036-0.087 Fetal alcohol syndrome: severe 0.177 0.117-0.255 Cannabis dependence 0.329 0.223-0.455 Amphetamine dependence 0.353 0.215-0.525 Cocaine dependence 0.376 0.235-0.553 Heroin and other opioid dependence 0.641 0.459-0.803 Anxiety disorders: mild 0.03 0.017-0.048 Anxiety disorders: moderate 0.149 0.101-0.210 Anxiety disorders: severe 0.523 0.365-0.684 Major depressive disorder: mild episode 0.159 0.107-0.223 Major depressive disorder: moderate episode 0.406 0.276-0.551 Major depressive disorder: severe episode 0.655 0.469-0.816 Bipolar disorder: manic episode 0.48 0.323-0.642 Bipolar disorder: residual state 0.035 0.021-0.055 Schizophrenia: acute state 0.756 0.571-0.894 Schizophrenia: residual state 0.576 0.399-0.756 Anorexia nervosa 0.223 0.151-0.313 Bulimia nervosa 0.223 0.150-0.310 Attention-deficit hyperactivity disorder 0.049 0.031-0.074 Conduct disorder 0.236 0.154-0.337 Asperger’s syndrome 0.11 0.073-0.157 Autism 0.259 0.177-0.362 Intellectual disability: mild 0.031 0.018-0.049 Intellectual disability: moderate 0.08 0.053-0.114 Intellectual disability: severe 0.126 0.085-0.176 Intellectual disability: profound 0.157 0.107-0.221 Hearing loss: mild 0.005 0.002-0.012 Hearing loss: moderate 0.023 0.013-0.038 Hearing loss: severe 0.032 0.018-0.051 Hearing loss: profound 0.031 0.018-0.049 Hearing loss: complete 0.033 0.020-0.052 Hearing loss: mild, with ringing 0.038 0.024-0.058 Hearing loss: moderate, with ringing 0.058 0.037-0.085 Hearing loss: severe, with ringing 0.065 0.041-0.094 Hearing loss: profound, with ringing 0.088 0.058-0.127 Hearing loss: complete, with ringing 0.092 0.061-0.134 Distance vision: mild impairment 0.004 0.001-0.010 Distance vision: moderate impairment 0.033 0.020-0.052 Distance vision: severe impairment 0.191 0.129-0.269 Distance vision blindness 0.195 0.132-0.272 Near vision impairment 0.013 0.006-0.024 Low back pain: acute, without leg pain 0.269 0.184-0.373 Low back pain: acute, with leg pain 0.322 0.219-0.447 Low back pain: chronic, without leg pain 0.366 0.248-0.499 Low back pain: chronic, with leg pain 0.374 0.252-0.506 Neck pain: acute, mild 0.04 0.023-0.064 Neck pain: acute, severe 0.221 0.150-0.305 Neck pain: chronic, mild 0.101 0.067-0.149 Neck pain: chronic, severe 0.286 0.197-0.398 Musculoskeletal problems: legs, mild 0.023 0.013-0.039 Musculoskeletal problems: legs, moderate 0.079 0.053-0.115 Musculoskeletal problems: legs, severe 0.171 0.117-0.240 Musculoskeletal problems: arms, mild 0.024 0.014-0.041 Musculoskeletal problems: arms, moderate 0.114 0.077-0.159 Musculoskeletal problems: generalised, moderate 0.292 0.197-0.410 Musculoskeletal problems: generalised, severe 0.606 0.421-0.771 Gout: acute 0.293 0.198-0.404 Amputation of finger(s), excluding thumb: long term, with treatment 0.03 0.018-0.048 Amputation of thumb: long term 0.013 0.006-0.025 Amputation of one arm: long term, with or without treatment 0.13 0.088-0.185 Amputation of both arms: long term, with treatment 0.044 0.028-0.067 Amputation of both arms: long term, without treatment 0.359 0.242-0.497 Amputation of toe 0.008 0.003-0.017 Amputation of one leg: long term, with treatment 0.021 0.011-0.035 Amputation of one leg: long term, without treatment 0.164 0.111-0.229 Amputation of both legs: long term, with treatment 0.051 0.032-0.076 Amputation of both legs: long term, without treatment 0.494 0.341-0.654 Burns of <20% total surface area without lower airway burns: short term, with or without treatment 0.096 0.062-0.140 Burns of <20% total surface area or <10% total surface area if head or neck, or hands or wrist involved: long term, with or without treatment 0.018 0.010-0.032 Burns of ≥20% total surface area: short term, with or without treatment 0.333 0.220-0.472 Burns of ≥20% total surface area or ≥10% total surface area if head or neck, or hands or wrist involved: long term, with treatment 0.127 0.086-0.183 Burns of ≥20% total surface area or ≥10% total surface area if head or neck, or hands or wrist involved: long term, without treatment 0.438 0.298-0.588 Lower airway burns: with or without treatment 0.373 0.248-0.521 Crush injury: short or long term, with or without treatment 0.145 0.093-0.211 Dislocation of hip: long term, with or without treatment 0.017 0.008-0.030 Dislocation of knee: long term, with or without treatment 0.129 0.087-0.178 Dislocation of shoulder: long term, with or without treatment 0.08 0.053-0.116 Other injuries of muscle and tendon (includes sprains, strains, and dislocations other than shoulder, knee, or hip) 0.009 0.004-0.018 Drowning and non-fatal submersion: short or long term, with or without treatment 0.288 0.191-0.403 Fracture of clavicle, scapula, or humerus: short or long term, with or without treatment 0.053 0.033-0.080 Fracture of face bone: short or long term, with or without treatment 0.173 0.111-0.257 Fracture of foot bones: short term, with or without treatment 0.033 0.019-0.053 Fracture of foot bones: long term, without treatment 0.033 0.019-0.052 Fracture of hand: short term, with or without treatment 0.025 0.013-0.043 Fracture of hand: long term, without treatment 0.016 0.008-0.028 Fracture of neck of femur: short term, with or without treatment 0.308 0.205-0.439 Fracture of neck of femur: long term, with treatment 0.072 0.047-0.105 Fracture of neck of femur: long term, without treatment 0.388 0.261-0.532 Fracture other than neck of femur: short term, with or without treatment 0.192 0.121-0.280 Fracture other than neck of femur: long term, without treatment 0.053 0.035-0.079 Fracture of patella, tibia or fibula, or ankle: short term,with or without treatment 0.087 0.055-0.127 Fracture of patella, tibia or fibula, or ankle: long term, with or without treatment 0.07 0.047-0.102 Fracture of pelvis: short term 0.39 0.257-0.545 Fracture of pelvis: long term 0.194 0.132-0.272 Fracture of radius or ulna: short term, with or without treatment 0.065 0.040-0.101 Fracture of radius or ulna: long term, without treatment 0.05 0.032-0.075 Fracture of skull: short or long term, with or without treatment 0.073 0.046-0.109 Fracture of sternum or fracture of one or two ribs: short term, with or without treatment 0.15 0.098-0.215 Fracture of vertebral column: short or long term, with or without treatment 0.132 0.085-0.195 Fractures: treated, long term 0.003 0.001-0.008 Injured nerves: short term 0.065 0.040-0.096 Injured nerves: long term 0.136 0.092-0.189 Injury to eyes: short term 0.079 0.050-0.118 Severe traumatic brain injury: short term, with or without treatment 0.235 0.156-0.331 Traumatic brain injury: long-term consequences, minor, with or without treatment 0.106 0.072-0.147 Traumatic brain injury: long-term consequences, moderate, with or without treatment 0.224 0.153-0.314 Traumatic brain injury: long-term consequences, severe,with or without treatment 0.625 0.444-0.789 Open wound: short term, with or without treatment 0.005 0.002-0.013 Poisoning: short term, with or without treatment 0.171 0.116-0.239 Severe chest injury: long term, with or without treatment 0.056 0.036-0.082 Severe chest injury: short term, with or without treatment 0.352 0.229-0.484 Spinal cord lesion below neck: treated 0.047 0.029-0.072 Spinal cord lesion below neck: untreated 0.44 0.290-0.588 Spinal cord lesion at neck: treated 0.369 0.243-0.513 Spinal cord lesion at neck: untreated 0.673 0.475-0.837 Abdominopelvic problem: mild 0.012 0.005-0.023 Abdominopelvic problem: moderate 0.123 0.083-0.176 Abdominopelvic problem: severe 0.326 0.219-0.451 Anaemia: mild 0.005 0.002-0.011 Anaemia: moderate 0.058 0.038-0.086 Anaemia: severe 0.164 0.112-0.228 Periodontitis 0.008 0.003-0.017 Dental caries:symptomatic 0.012 0.005-0.023 Severe toothloss 0.072 0.048-0.103 Disfigurement: level 1 0.013 0.006-0.025 Disfigurement: level 2 0.072 0.048-0.103 Disfigurement: level 3 0.398 0.271-0.543 Disfigurement: level 1 with itch or pain 0.029 0.016-0.048 Disfigurement: level 2, with itch or pain 0.187 0.125-0.264 Disfigurement: level 3, with itch or pain 0.562 0.394-0.725 Generic uncomplicated disease: worry and daily medication 0.031 0.017-0.050 Generic uncomplicated disease: anxiety about diagnosis 0.054 0.033-0.082 Iodine-deficiency goitre 0.2 0.134-0.283 Kwashiorkor 0.055 0.033-0.085 Severe wasting 0.127 0.081-0.183 Speech problems 0.054 0.034-0.081 Motor impairment: mild 0.012 0.005-0.022 Motor impairment: moderate 0.076 0.050-0.109 Motor impairment: severe 0.377 0.251-0.518 Motor plus cognitive impairments: mild 0.054 0.033-0.084 Motor plus cognitive impairments: moderate 0.221 0.141-0.314 Motor plus cognitive impairments: severe 0.425 0.286-0.587 Rectovaginal fistula 0.492 0.330-0.660 Vesicovaginal fistula 0.338 0.228-0.467